Annual cost ranges by treatment type
Visual at-a-glance comparison of annual treatment costs. Uninsured (red) vs insured (green) ranges. Median values shown as horizontal lines. Hover bars for detail.
HRT (FDA-approved)
Uninsured: $540/yr · Insured: $120/yr
Generic estradiol patch + oral progesterone tier 1 for most plans. Cash-pay reasonable too.
HRT (compounded)
Uninsured: $1,020/yr · Insured: $1,020/yr
Insurance rarely covers compounded. Premium for customization.
GLP-1 (Wegovy/Zepbound)
Uninsured: $14,400/yr · Insured: $900/yr
Massive gap insured vs uninsured. Prior auth often required.
GLP-1 (compounded)
Uninsured: $4,200/yr · Insured: $4,200/yr
Cash-pay only. FDA shortage list ending narrows compounding window.
PCOS (metformin + spironolactone)
Uninsured: $420/yr · Insured: $60/yr
Both generics tier 1. Cheap even cash-pay.
Fertility (IUI prep)
Uninsured: $3,000/yr · Insured: $1,200/yr
Highly variable by state mandate. IVF cycle separate ($15-25k per).
Thyroid (levothyroxine)
Uninsured: $300/yr · Insured: $60/yr
Cheap generic. Annual labs add $50-200.
Non-hormonal vasomotor (fezolinetant/SSRI)
Uninsured: $3,600/yr · Insured: $600/yr
Fezolinetant (Veozah) ~$550/mo cash. SSRIs generic <$15/mo.
Plan around the costs
Budget planner
Mix-and-match treatments to see total annual estimate.
Insurance coverage matrix
Check whether your insurer covers specific treatments.
Cost-per-outcome
Which brands deliver best outcome per dollar?
Methodology
Ranges derived from reviewed brand directory + insurance formulary tier data. Insured values assume PPO with tier 2 copay; HMO + high-deductible plans may differ. Lab costs, consult fees, and one-time procedures excluded — focus is recurring medication cost.